| Name | Category | Year | Motivation |
|---|
| Sydney Brenner | Medicine | 2002 | "for their discoveries concerning genetic regulation of organ development and programmed cell death'" |
| John M. Coetzee | Literature | 2003 | "who in innumerable guises portrays the surprising involvement of the outsider" |
| Allan M. Cormack | Medicine | 1979 | "for the development of computer assisted tomography" |
| Frederik Willem de Klerk | Peace | 1993 | "for their work for the peaceful termination of the apartheid regime, and for laying the foundations for a new democratic South Africa" |
| Nadine Gordimer | Literature | 1991 | "who through her magnificent epic writing has - in the words of Alfred Nobel - been of very great benefit to humanity" |
| Michael Levitt | Chemistry | 2013 | "for the development of multiscale models for complex chemical systems" |
| Nelson Mandela | Peace | 1993 | "for their work for the peaceful termination of the apartheid regime, and for laying the foundations for a new democratic South Africa" |
| Max Theiler | Medicine | 1951 | "for his discoveries concerning yellow fever and how to combat it" |
| Desmond Mpilo Tutu | Peace | 1984 | |